- Cistus ladanifer L. (Cistaceae). Source = gum (labdanum gum) bằng cách immerse leaves + terminal branches trong boiling water. Labdanum oil steam distilled từ gum. Classical amber-accord fixative.
- Cross-reference rail: Cistus oil (sản phẩm khác — steam distilled trực tiếp từ leaves/branches, KHÁC constituent ratios). Labdanum-oil và cistus-oil là 2 sản phẩm KHÁC NHAU từ SAME Cistus ladanifer species.
- Chemistry (Lawrence 1989, 1999d): α-Pinene 4.9–44.0% + 3-Phenylpropionic acid 0–22.2% + Camphene 1.4–7.0% + p-Cymene 2.1–6.3% + Caryophyllene oxide 0–4.4% + Viridiflorol 1.4–3.7%. Huge α-pinene range (9-fold variation) — chemotype-driven.
- Hazards: None known. Contraindications: None known. Opdyke 1976 p.335 — 8%/25 volunteer non-irritating + non-sensitizing; non-phototoxic. Acute oral LD50 rat 8.98 g/kg (very low toxicity). LD50 rabbit dermal >5 g/kg.
- Pinocamphone-GABA rail (positive framing): Pinocamphone <1.3% does NOT require GABA-A inhibitory neurotoxicity restriction. High α-pinene content potentiate GABA-A (opposing direction) → functionally neutralize pinocamphone signal. KHÔNG known carcinogens. Labdane diterpene (labdane + sclareol) stay mostly trong gum/absolute, partial trong steam-distilled oil.
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