Thận trọngNốt hương đầu — giữaGreen-herbaceous-earthy

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Tổng Quan

Danh pháp khoa học: Angelica archangelica L.
Họ thực vật: Apiaceae
Phương pháp chiết xuất: Chưng cất hơi nước
Phân loại nốt hương: Nốt Top/Middle

Tình trạng tại Việt Nam

Xem chi tiết

Phân loại nốt

Đầu — Giữa

Độ bền trên da

2–4 giờ

Họ hương

Green-herbaceous-earthy

Mô tả hương

Rễ cây trầm sâu ẩm đất, cay nhẹ thảo xanh hoang dã, hơi thở thông khô mát lạnh, musk ấm nhung mềm mại, cổ kính lặng yên

Cường độ hương

3/5

Da khô

3/5

Da dầu/mụn

2/5

Da lão hóa

3/5

Da thường

3/5

Da nhạy cảm

1/5

Da hỗn hợp

2/5

Nhập khẩu

Tên gọi tại Việt Nam

Tinh dầu Bạch chỉ Âu (Angelica Root — European)

An Toàn

Giới hạn bôi da

0.8%

Theo hồ sơ an toàn (người lớn)

Bảo quản

Bảo quản nơi tối, mát

Xem hồ sơ an toàn chi tiết

Pha Chế & Hòa Hợp

sedative / anxiolytic

Monoterpene hydrocarbon fraction (α-phellandrene, β-phellandrene, δ-3-carene per Kerrola 1994 and Chalchat 1991) may modulate GABA-A receptor activity, a class-typical CNS-depressant effect of monoterpene-rich Apiaceae oils; no angelica-specific human mechanistic data confirmed.

Ref: Tisserand & Young 2014, Ch.13 p.440; composition basis: Kerrola (1994); Chalchat (1991)

carminative / antispasmodic

Phthalide constituents (ligustilide, 3-n-butylidenephthalide) shared with Apiaceae peers (celery, lovage) exert smooth-muscle spasmolytic activity on gastrointestinal tone; class-extrapolation from confirmed phthalide activity in peer species.

Ref: class-extrapolation from celery-seed / lovage-root (phthalide class); Tisserand & Young 2014, Ch.13 p.440

expectorant / mucolytic

Monoterpene hydrocarbons (α- and β-phellandrene, limonene per Kerrola 1994; Chalchat 1991) promote mucociliary clearance and reduce mucous viscosity via surface-active effects, a class-level action across monoterpene-rich EOs.

Ref: Tisserand & Young 2014, Ch.13 p.440; composition basis: Kerrola (1994); Chalchat (1991)

CYP enzyme inhibitor (drug-interaction risk)

Furanocoumarins (bergapten, psoralen, oxypeucedanin) act as mechanism-based irreversible inhibitors of CYP3A4, CYP1A2, CYP2A6, and CYP2B6; analogous to the grapefruit juice/bergamottin CYP3A4 effect (Bailey 1998), posing real drug-interaction risk at therapeutic doses.

Ref: Koenigs (1997); Bailey (1998) [paradigmatic CYP3A4 mechanism]; Ch.14 Furanocoumarin composite profile [via B216]

lymphatic / circulatory tonic

Traditional aromatherapy attribution shared across monoterpene-rich Apiaceae oils; proposed mechanism involves mild stimulation of lymphatic and venous circulation via topical application, though no controlled evidence confirms this for angelica root specifically.

Ref: Tisserand & Young 2014, Ch.13 p.440

Chống viêm

β-Caryophyllene sesquiterpene, plausible in Apiaceae root chemistry, acts as selective CB2 receptor agonist modulating NF-κB inflammatory cascades; class-extrapolation — β-caryophyllene presence in this oil not confirmed by available Kerrola/Chalchat citations.

Ref: class-extrapolation from β-caryophyllene sesquiterpene class (e.g. copaiba, black pepper); Tisserand & Young 2014, Ch.13 p.440

AI-summary

No RCT-grade clinical evidence has been located for Angelica Root essential oil as a therapeutic agent. The most robust pharmacological data are in vitro: Koenigs (1997) demonstrated mechanism-based inhibition of CYP3A4, CYP1A2, CYP2A6, and CYP2B6 by angelica root furanocoumarins — a drug-interaction risk signal rather than a therapeutic claim. The photosensitization mechanism via bergapten/psoralen UV-A photoadduct formation is well-characterised (T&Y Ch.14 Bergapten profile). Opdyke (1975) confirmed non-sensitization in a 25-volunteer HRIPT at 4%, with high acute oral LD50 (rat 11 g/kg) and dermal LD50 >5 g/kg, establishing a safety baseline. Traditional aromatherapy use for digestive, respiratory, and nervous system support is documented in T&Y Ch.13 p.440 but lacks controlled human trial validation.

Narrative

Tâm trạng: Đặt vững, Làm dịu

lo âuexhaustionnervous tensionkiên cườngintrospectionspiritual protection

Chakra

Luân xa Gốc

Ngũ hành

Thổ

Phương pháp	Liều lượng	Ghi chú
Diffusion	2–4 drops in 100 ml water (ultrasonic) or 2–3 drops neat (cold-air diffuser)	Preferred route — no phototoxicity risk via inhalation. Suitable for relaxation and respiratory support. Diffuse ≤30 min/session; ventilate room. Contraindicated around children.
Topical massage	0.5–0.8% in carrier oil (3–5 drops per 30 ml carrier)	PHOTOTOXIC: avoid UV exposure on treated skin ≥12 h post-application, or apply only to covered areas. Hard cap 0.8%. Do not use on children. Avoid face/neck/décolletage before sun exposure.
Steam inhalation	1–2 drops in bowl of hot water	Head-over-bowl, 5–10 min with eyes closed. No phototoxic risk via this route. Not suitable for children.
Bath	2–3 drops pre-dispersed in 1 tsp unscented bath gel before adding to water	PHOTOTOXIC: avoid UV exposure on bathed skin ≥12 h. Pre-disperse in emulsifier to prevent neat-oil skin contact. Avoid in children.

Dầu nền phù hợp

JojobaLiquid wax with exceptional oxidative stability — ideal pairing with an EO requiring careful storage; non-comedogenic and skin-neutral, suits the conservative 0.8% dermal cap.

Sweet Almond OilLight, emollient, oleic-acid-rich carrier that spreads well for massage and supports circulatory/lymphatic applications without overshadowing the delicate herbal-musky scent profile.

Sunflower OilAffordable, linoleic-rich carrier with good skin penetration; practical base for high-volume massage blends at the low 0.8% cap where carrier volume substantially exceeds EO.

Rosehip Seed OilRich in linoleic/linolenic acids; suits mature skin positioning. Use night-only or on covered skin given phototoxicity — do not pair with sun exposure.

Kết hợp tốt với

GỗNhựa câyHerbaceousCayXanh tươi

Blend kinh điển

Vetiver— Both oils share a deep earthy-rooty signature that anchors a grounding base accord with extraordinary dry-down tenacity.

Frankincense— Frankincense's balsamic resinous warmth lifts angelica's austere darkness into a meditative, spiritually anchored composition.

Black Pepper— Shared phellandrene-class monoterpenes create a seamless bridge between angelica's earthy depth and black pepper's dry spicy sparkle.

Clary Sage— Clary sage's herbaceous-balsamic sweetness softens angelica's severity, forming a calming accord for nervous exhaustion.

[Tisserand & Young] Ch.13 p.440

[Kerrola] angelica root GC composition [via B216]

[Opdyke] angelica root oil 4%/25 volunteers non-sensitizing + LD50 rat 11 g/kg + dermal rabbit >5 g/kg [via B216]

[Koenigs] furanocoumarin CYP3A4 + CYP1A2 + CYP2A6 + CYP2B6 inhibition [via B216]

[Ch.14 Bergapten profile] photosensitization mechanism + PUVA therapy [via B216]

[Ch.14 Furanocoumarin composite profile] CYP inhibition mechanism, phototoxic equivalents [via B216]

[Bailey] grapefruit juice + bergamottin + CYP3A4 mechanism-based inhibition (paradigmatic)

[IFRA Standard] bergapten + psoralen-class restrictions in fragrance (categorical)

Kỹ Thuật

Tổng định danh

~90–98%

Hợp chất

Khoảng %

α-Pinene

14.0–31.1%

β-Phellandrene

10.0–24.0%

α-Phellandrene

2.0–14.0%

δ-3-Carene

8.0–13.8%

(+)-Limonene

7.5–15.0%

β-Pinene

1.3–4.3%

p-Cymene

0.5–2.4%

Myrcene

0.5–2.0%

Sabinene

vết–1.5%

Furanocoumarins (TỔNG)

0.2–2.0%

↳ Xanthotoxin (8-MOP)

0.1–0.8%

↳ Bergapten (5-MOP)

0.05–0.5%

↳ Imperatorin

0.05–0.4%

↳ Angelicin (isobergapten)

0.02–0.3%

↳ Oxypeucedanin + Psoralen

vết–0.2%

Pentadecanolide (macrocyclic lactone dạng xạ hương)

0.1–1.5%

Tridecanolide

vết–0.8%

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